This listing was posted on jobRxiv.
Researcher - Department of Oncology - Obeng Lab
Location:
Memphis
Description:
We are seeking a highly motivated individual with an interest in biomedical research. Successful applicants will have an interest in basic and translational research and respond well to a busy and dynamic lab environment. Overview The Obeng Laboratory is part of the Department of Oncology at St. Jude Children's Research Hospital in Memphis, TN. Research in the Obeng lab centers on the pathogenesis of myeloid malignancies, including myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). We are investigating how acquired somatic mutations in hematopoietic stem cells lead to clonal hematopoiesis and malignant transformation.The major interests of the Obeng lab are (1) determining how mutations in components of the mRNA spliceosome and epigenetic regulators cooperate to cause clonal hematopoiesis and leukemia (2) identifying and studying novel treatments that selectively target mutant stem cells and (3) determining the incidence and clinical significance of clonal hematopoiesis of indeterminate potential (CHIP) in pediatric cancer survivors. Job Responsibilities: The ideal candidate will utilize state-of-the-art techniques in genetics, molecular biology, and cell biology to characterize in vitro and in vivo models of human diseases with a particular focus on RNA splicing factor mutations and their relationship to MDS and leukemia. You will have the opportunity to develop and lead projects using several cutting-edge model systems, including isogenic immortalized cell lines generated using CRISPR-Cas9 gene editing, novel xenograft and transgenic in vivo systems, and primary patient samples. In this position, you will gain extensive experience and training in genomics, stem cell biology, and pre-clinical study development. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Will also consider current students with an anticipated graduation date within 3 months of application. Verification of degree is required prior to start date. Minimum Experience: No experience required. Applicants with some exposure to an appropriate scientific field such as cellular or molecular biology are encouraged to apply. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $24.00 - $42.00 per hour for the role of Researcher - Department of Oncology - Obeng Lab.Explore our exceptional benefits ! Diversity, Equity and Inclusion St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment .Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Company:
St. Jude Children's Research Hospital
Posted:
May 10 on jobRxiv
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More About this Listing: Researcher - Department of Oncology - Obeng Lab
Researcher - Department of Oncology - Obeng Lab is a Research Research Associate Job at St. Jude Children's Research Hospital located in United States. Find other listings like Researcher - Department of Oncology - Obeng Lab by searching Oodle for Research Research Associate Jobs.
Researcher - Department of Oncology - Obeng Lab is a Research Research Associate Job at St. Jude Children's Research Hospital located in United States. Find other listings like Researcher - Department of Oncology - Obeng Lab by searching Oodle for Research Research Associate Jobs.